Side Effects of Extracorporeal Shock-Wave Exposure in Patients Treated by Extracorporeal Shock-Wave Lithotripsy for Upper Urinary Tract Stone
- 1 January 1986
- journal article
- research article
- Published by Elsevier in European Urology
- Vol. 12 (5), 308-313
- https://doi.org/10.1159/000472644
Abstract
The side effects of shock-wave exposure on patients treated by extracorporeal shock-wave lithotripsy were analyzed by measuring chemical substances including cell-escaped enzymes in the blood and urine. Free hemoglobin, glutamic oxaloacetic transaminase (GOT) and lactate dehydrogenase (LDH) increased as a function of shock-wave count. Total bilirubin, GOT and LDH reached a peak on the 1st postoperative day and decreased to pretreatment values by the 4th day. Creatine phosphokinase and myoglobin also significantly increased on the 1 st postoperative day but returned to pretreatment levels by the 4th day. The urinary ratio of N-acetyl-ß-d-glucosaminase to creatinine significantly increased after treatment and was still high on the 4th day. These results suggest that significant hemolysis and myolysis developed owing to shock-wave exposure, and that the kidney was damaged to some extent. Therefore, these side effects must be taken into account in determining the dose and frequency of treatment.Keywords
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