Effect of Gossypol on Boar Spermatozoa in Vitro
- 1 January 1981
- journal article
- research article
- Published by Taylor & Francis in Archives of Andrology
- Vol. 7 (1), 85-88
- https://doi.org/10.3109/01485018109009381
Abstract
Gossypol, the active component in cottonseed oil, inhibits spermatogenesis in many mammals. Gossypol enhanced respiration and abolished forward motility of boar spermatozoa. The effective concentration was 10-5 M, similar to that reported in its uncoupling of oxidative phosphorylation in rat liver mitochondria. Its antifertility effect may be a combination of the effect on the developing spermatids as well as that on spermatozoal motility.Keywords
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