SELECTION FOR HIGH MUTATION RATES IN CHEMOSTATS
Open Access
- 1 June 1974
- journal article
- research article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 77 (2), 169-184
- https://doi.org/10.1093/genetics/77.2.169
Abstract
Competition experiments in chemostats show that mutator populations of Escherichia coli are more fit than wild type. The increased fitness can be explained by the appearance of new mutants better adapted to the chemostat environment. Fitness values vary between chemostats and are strongly correlated (P < 0.001) with fluctuations in population density.Keywords
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