Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines
- 31 March 2006
- journal article
- Published by Elsevier in Molecular Immunology
- Vol. 43 (8), 1221-1231
- https://doi.org/10.1016/j.molimm.2005.07.015
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- The carboxyl terminus of the chemokine receptor CCR3 contains distinct domains which regulate chemotactic signaling and receptor down‐regulation in a ligand‐dependent mannerEuropean Journal of Immunology, 2005
- On the Mechanism and Significance of Ligand-induced Internalization of Human Neutrophil Chemokine Receptors CXCR1 and CXCR2Journal of Biological Chemistry, 2004
- Molecular characterization of the chemokine receptor CXCR3: evidence for the involvement of distinct extracellular domains in a multi‐step model of ligand binding and receptor activationEuropean Journal of Immunology, 2003
- The CC Chemokine Eotaxin (CCL11) Is a Partial Agonist of CC Chemokine Receptor 2bJournal of Biological Chemistry, 2001
- NMR Solution Structure and Backbone Dynamics of the CC Chemokine Eotaxin-3,Biochemistry, 2001
- Identification of a Potent and Nonpeptidyl CCR3 AntagonistBiochemical and Biophysical Research Communications, 2001
- A Small Molecule Antagonist of Chemokine Receptors CCR1 and CCR3Published by Elsevier ,2000
- NMR Solution Structure and Receptor Peptide Binding of the CC Chemokine Eotaxin-2,Biochemistry, 2000
- The N-terminal Extracellular Segments of the Chemokine Receptors CCR1 and CCR3 Are Determinants for MIP-1α and Eotaxin Binding, Respectively, but a Second Domain Is Essential for Efficient Receptor ActivationJournal of Biological Chemistry, 1998
- Eotaxin: Cloning of an Eosinophil Chemoattractant Cytokine and Increased mRNA Expression in Allergen-Challenged Guinea-Pig LungsBiochemical and Biophysical Research Communications, 1994