Effect of Snake Venom upon Membrane Adenosine Triphosphatase of Human Erythrocyte

Abstract

Human erythrocyte ghosts prepared by the Post''s method were incubated with heated venom (100[degree]C, 8 min, at pH 7.5) for 17 hours at 4[degree]C. The phospholipase-treated ghosts did not show Na-K-dependent, oubain-sensitive adenosine triphosphatase (ATPase) any more, while oubain-insensitive, Na-K-independent ATPase was not affected.