Clinical Trials of Hepatitis B Immune Globulin

Abstract
The National Blood Resource Branch of the National Heart and Lung Institute initiated on July 1, 1972, controlled clinical studies to evaluate the efficacy of hepatitis B immune globulin (HBIC) for the prevention and treatment of hepatitis Type B. Three patient populations are being investigated: subjects with acute fulminant hepatitis; persons with a known, accidental parenteral exposure to hepatitis B antigen (HBAg) contained in blood or blood products; and patients and staff newly arrived on chronic renal-dialysis units. Co-ordinating centers have been established for each patient population to be studied. Working with these centers, in clinical trials investigators affiliated with . . .