A gene controlling segregation of the Bacillus subtilis plasmid pC194
- 1 March 1985
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 198 (3), 427-431
- https://doi.org/10.1007/bf00332934
Abstract
Plasmid pC194-1, a mutant of pC194, and chimeric derivatives of pC194-1 are segregationally unstable in B. subtilis. Such instability could be enhanced by exposure of pC194-1-carrying cells to methyl methanesulfonate. pC194-1 is distinct from pC194 in the addition of two A:T base pairs within the previously defined D region of pC194. Complementation experiments between pC194-1 and other plasmids suggest that the mutation of pC194-1 interferes with the production of a diffusible gene product required for plasmid maintenance.This publication has 37 references indexed in Scilit:
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