History.— Dec. 18, 1907, the patient, then a child of 2 years, was brought to me by his father. The child had been suffering for a time with numerous subcutaneous abscesses, concerning the nature of which he had consulted numerous medical advisers, the majority of whom considered tuberculosis or syphilis as the possible etiologic factor. The father stated that, in October, 1907, when two years and two months old, the child began to walk lame and shortly afterward his right ankle became red and swollen. A few days later an abscess was discovered on the back of the head. Within a few weeks many abscesses developed on the scalp, in the neighborhood of the joints of the knees, toes, shoulders, elbows and thumbs, and over both upper eyelids. These were opened from time to time by Dr. Kellogg of Bakersfield and the pus evacuated. The child now failed rapidly, had