A Study of Thrombopoiesis in Induced Acute Thrombocytopenia
Open Access
- 1 January 1960
- journal article
- research article
- Published by American Society of Hematology in Blood
- Vol. 15 (1), 174-185
- https://doi.org/10.1182/blood.v15.1.174.174
Abstract
Thrombocytopenia was induced in rats by exchange transfusions of platelet-free blood. Cytoplasmic changes rather than gross quantitative increase were noted in the megakaryocytes. After a latent period of 2 days the rate of appearance of thrombocytes increased, and after a temporary thrombocytosis the normal level was reestablished by the 7th day. The spleen appears to influence thrombocyte number through changes in the rate of thrombopoiesis.This publication has 6 references indexed in Scilit:
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