Clinical Characteristics and Response to Therapy in Egyptian Children Infected with Schistosoma haematobium
- 1 June 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 149 (6), 998-1004
- https://doi.org/10.1093/infdis/149.6.998
Abstract
Forty-one Egyptian students with infections due to Schistosoma haematobium, who were selected by results of a urine screening examination, were evaluated for morbidity and response to chemotherapy. Symptoms associated with infection were hematuria, dysuria, and swimmer's itch. A positive correlation existed between the intensity of infection and frequency of exposure to water. Laboratory abnormalities included eosinophilia (41), anemia (9), hematuria (38), pyuria (33), and proteinuria (8). Three of 26 subjects had abnormalities intravenous pyelograms: hydroureter, bladder polyp, and bladder calcification. The bladder polyp was noted also by sonography. Cure rates were 66.7% in 18 subjects treated with two 10-mg/kg doses of trichlorfon and were 89.5% in 19 subjects given three doses. Those not cured had an average reduction in ova excretion of 96%. Follow-up at 12 months of 33 subjects showed that nine had S. haematobium ova in urine, although 75% admitted to exposure to canal or irrigation water in the interim.This publication has 23 references indexed in Scilit:
- Field trial of metrifonate in the treatment and prevention of Schistosomiasis infection in manPathogens and Global Health, 1977
- Schistosomal Polyposis of the Urinary Bladder *The American Journal of Tropical Medicine and Hygiene, 1977
- Surgical Pathology of Schistosomal Obstructive Uropathy: a Clinicopathologic Correlation *The American Journal of Tropical Medicine and Hygiene, 1977
- Schistosomal Ulceration of the Urinary Bladder *The American Journal of Tropical Medicine and Hygiene, 1977
- Hydronephrosis, Bacteriuria, and Maximal Urine Concentration in Urinary SchistosomiasisAnnals of Internal Medicine, 1971
- Urinary schistosomiasis in Ghana: A report of 53 cases, with special reference to pyelographic and cystoscopic abnormalitiesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1967
- Urological complications of endemic schistosomiasis in schoolchildren Part 2. Donge school, ZanzibarTransactions of the Royal Society of Tropical Medicine and Hygiene, 1966
- Schistosoma haematobiuminfection in NigeriaPathogens and Global Health, 1965
- Schistosoma haematobiuminfection in NigeriaPathogens and Global Health, 1965
- Urological complications of endemic schistosomiasis in school-childrenTransactions of the Royal Society of Tropical Medicine and Hygiene, 1965