Chloramphenicol and phenobarbitone--a drug interaction.
- 1 January 1979
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 54 (1), 76-77
- https://doi.org/10.1136/adc.54.1.76
Abstract
Infants (2) with bacterial meningitis who were treated with phenobarbitone and high-dose chloramphenical showed progressive falls in the peak blood levels of chloramphenicol. A standard chloramphenicol dose of 50 mg/kg daily would have produced subtherapeutic blood levels after only a few days. The importance of measuring serial blood chloramphenicol concentrations is stressed.This publication has 11 references indexed in Scilit:
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