A Convenient Procedure for Esterification of Thermally Unstable Carboxylic Acids
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 6 (2), 89-92
- https://doi.org/10.1080/00397917608072615
Abstract
There are many new methods for esterifying carboxylic acids but some have specific limitations such as harsh conditions, inconvenience of procedure, expense and inaccessibility of reagents1-6 we have prepared several novel bicyclic β–keto acids as intermediates for the synthesis of heterocyclic systems. Since these β–keto acids readily decarboxylate on heating, esterification by a simple low temperature procedure was necessary.Keywords
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