Ketazolam and Diazepam in Anxiety: A Controlled Study

Abstract

Ketazolam (both in once daily and 3 times per day dosage), diazepam and placebo were compared for effectiveness in relieving anxious symptomatology in a clinical trial conducted with 222 anxious, non-psychotic outpatients. Improvement occurred early in treatment, that ketazolam was equally effective in both the once-daily and 3 times per day dosage and ketazolam was similar in effect to diazepam. Ketazolam (both-once daily and 3 times per day and diazepam were significantly (P < 0.05) better than placebo in alleviating symptoms of anxiety as measured by the Hamilton Anxiety Scale, the Covi Anxiety Scale and a physician-rated measure of global improvement.