The Effect of Long Term Phenothiazine Therapy on Plasma Prolactin
- 1 July 1975
- journal article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 127 (1), 71-74
- https://doi.org/10.1192/bjp.127.1.71
Abstract
Summary: Plasma prolactin has been estimated in 69 psychiatric in-patients receiving either thioridazine (20–300 mg./day) or chlorpromazine (50–200 mg./day) or other phenothiazines. A homologous radioimmuno-assay was used which depends on an antiserum to human amniotic prolactin. Prolactin levels were significantly increased in these patients compared with control patients, and were dose related. Simultaneous estimation of growth hormone revealed normal levels.Keywords
This publication has 8 references indexed in Scilit:
- The Effects of Phenothiazines on Endocrine Function: IThe British Journal of Psychiatry, 1974
- Plasma prolactin and breast cancerCancer, 1974
- Plasma prolactin in breast cancerEuropean Journal of Cancer (1965), 1973
- Radioimmunoassay for Human Pituitary Prolactin, Using Antiserum against an Extract of Human Amniotic FluidHormone Research, 1973
- PROLACTIN AND BREAST CANCERThe Lancet, 1972
- Human Prolactin: 24-Hour Pattern with Increased Release during SleepScience, 1972
- Cancer mortality among patients in New York mental hospitalsCancer, 1967
- A Sensitive Double Antibody Immunoassay for Human Growth Hormone in PlasmaNature, 1964