Recombinant antibodies possessing novel effector functions
- 1 December 1984
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 312 (5995), 604-608
- https://doi.org/10.1038/312604a0
Abstract
The introduction into [mouse] lymphocytes of Ig gene DNA that was manipulated in vitro allows the production of novel antibodies. In this way, cells lines were established that secrete hapten-specific antibodies in which the Fc portion was replaced with an active enzyme moiety or with polypeptide displaying c-myc antigenic determinants.This publication has 14 references indexed in Scilit:
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