HISTOCHEMICAL STUDIES ON THE DISTRIBUTION OF SIMPLE ESTERASE, SPECIFIC AND NON-SPECIFIC CHOLINESTERASE IN TRIGEMINAL GANGLION CELLS OF RAT

Abstract

The present study incorporates a detailed histochemical investigation on the distribution of simple esterase, specific and non-specific cholinesterases at the intracellular level among trigeminal ganglion cells and other associated structures. Preparations for simple esterase have invariably provided a cyto-plasmic reaction in all the trigeminal ganglion cells. Furthermore there are indications of cyclic distribution of the enzyme in these cells-some show a perinuclear concentration, others show a general distribution. The significance of such a topographical arrangement in relation to various cytoplasmic organelles has been discussed. Specific cholinesterase reaction provides a great variation. Some cells show a cytoplasmic reaction; others show exclusive localization at the peri- pheral parts and yet some are negative. The processes arising from the trigeminal ganglion cells and the bulb-like expansions emerging from the processes are positive for specific cholinesterase. An attempt has been made in coordinating the various patterns of specific cholinesterase distribution among different cells with their possible physiological aspects. Non-specific cholinesterase is solely restricted to the periphery of the cells. The physiological significance of such a localization in relation to specific cholinesterase has also been discussed.