DEOXYRIBONUCLEIC ACID (DNA) autosensitivity of the type described in 1961 by Levin and Pinkus is a syndrome of two principle parts: (1) recurrent, painful, and ecchymotic nodules and plaques on the extremities, and (2) immediate hypersensitivity to injections of DNA, localized to the skin of the affected areas while the same test on the skin of the flank is nonreactive. Other cases have been reported of this recently described and peculiar syndrome.2,3All cases occurred in women, in whom the general health was not affected. Significantly, adequate treatment with chloroquine gave unequivocal relief of symptoms in all these patients. Report of a Case Our patient was a 13-year-old girl in whom persistent painful swellings developed on the dorsum of the left hand first in February 1964, after a bump with a piece of stovewood. Impressive ecchymotic nodules progressed steadily up the left arm almost to the shoulder and, about