Growth of Cancer Tissue in the Yolk Sac of the Chick Embryo

Abstract

Growth of tumor tissue within the yolk sac of de-veloping chick embryos was obtained by inj. of the yolk with a suspension of tissue of mammary carcinoma transplants of the DBA and C3H strains of mice. Inj. was made by use of a 20-gauge needle. Tumor tissue removed after 17 days'' total incubation of the eggs conformed in appearance with the mouse-grown tissue and grew readily when transplanted back into mice.