DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
Open Access
- 25 March 2010
- journal article
- research article
- Published by Springer Nature in Molecular Cancer
- Vol. 9 (1), 68
- https://doi.org/10.1186/1476-4598-9-68
Abstract
Breast cancer is the most frequent cancer in women and consists of a heterogeneous collection of diseases with distinct histopathological, genetic and epigenetic characteristics. In this study, we aimed to identify DNA methylation based biomarkers to distinguish patients with locally advanced breast cancer who may benefit from neoadjuvant doxorubicin treatment.Keywords
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