The A and B Subgroups of Human Respiratory Syncytial Virus: Comparison of Intergenic and Gene-overlap Sequences
- 1 November 1988
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 69 (11), 2901-2906
- https://doi.org/10.1099/0022-1317-69-11-2901
Abstract
Intergenic and flanking gene regions for the 1C-1B, Ib-N, N-P, M-1A, G-F and F-22K gene junctions of respiratory syncytial virus strain 18537, representing antigenic subgroup B, were determined by dideoxynucleotide sequencing of polycistronic cDNAs and mRNAs. Comparison with their counterparts from the subgroup A strain A2 showed that the intergenic sequences were not conserved within or between the strains. Flanking non-coding gene sequences also were generally not conserved except for the highly conserved gene-start and gene-end transcription signals. The sequence of the overlap between the 22K and L genes was conserved almost exactly between the two subgroups.This publication has 15 references indexed in Scilit:
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