A Biomechanical, Scanning Electron, and Light Microscopic Evaluation

Abstract

Two currently available brands of PTFE [polytetrafluoroethylene] grafts (Goretex and Impra) were studied in a canine femoral artery model to determine whether changes in the manufacturing processes of the 2 grafts, which increased their strength, had altered the biophysical properties and the histological reactivity of either graft. Both grafts were similar except for differences in their suturability. Their in vivo dynamic compliances were almost identical (1.2 .+-. 0.35 vs. 1.2 .+-. 0.45). Scanning electron microscopy showed endothelialization of the grafts only adjacent to the anastomoses, and light microscopy demonstrated similar degrees of histologic incorporation by the host tissues, though of slower tempo than that previously described. These results are examined and discussed with regard to the suitability of this model for characterizing new arterial prostheses of small to medium diameter.