HL-A Antigens in Pemphigus
- 1 July 1973
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 108 (1), 53-55
- https://doi.org/10.1001/archderm.1973.01620220025006
Abstract
We studied the frequency of 20 human leukocyte (HL-A) alloantigens in 18 patients with pemphigus. HL-A13 was significantly increased as compared to a normal racial control group. Five of the 18 patients (28%) had HL-A13, whereas only 10 of 251 controls (4%) had the same antigen. Sera from patients did not react with their own lymphocytes nor did they have any anti-HL-A antibodies in lymphocytotoxicity tests. Anti HL-A sera did not react with the pemphigus interepithelial antigen in an indirect immunofluorescent test.Keywords
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