The fine structure of the ventricular surface of the area postrema of the cat, with particular reference to supraependymal structures

Abstract

The ependymal surface of the feline area postrema (AP) has been examined with the scanning and transmission electron microscopes. Particular attention was paid to the distribution and structure of supraependymal (SE) cells which have not been described before on this organ. A population of SE cells was found consistently on the cat AP; they were grouped most frequently toward the caudal aspect of the organ. Their structure bears a great resemblance to that of macrophages, containing: (1) many small apical vacuoles, (2) numerous lysosomes, and (3) phagosome‐like bodies. Arrays of microvillous tufts and also singly‐occurring microvilli are features of the unciliated ependymal surface of the organ. Tufts are often found in very close proximity to superficial blood vessels which are characteristically surrounded by large perivascular spaces.