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A self-cleaving DNA nucleoside
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A self-cleaving DNA nucleoside
A self-cleaving DNA nucleoside
Vineet Gupta
Vineet Gupta
EK
Eric T. Kool
Eric T. Kool
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1 January 1997
journal article
research article
Published by
Royal Society of Chemistry (RSC)
in
Chemical Communications
No. 15
,
p.
1425-1426
https://doi.org/10.1039/a700626h
Abstract
An allyl-modified nucleoside has been shown to self-alkylate and depurinate on treatment with iodine and heat; placement in DNA strands yields site-directed cleavage of the DNA.
Keywords
TREATMENT
NUCLEOSIDE
CLEAVING DNA
ALKYLATE
CLEAVAGE
DEPURINATE
HEAT
STRANDS
IODINE
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Cited by 6 articles