An Inhibitory Protein of Escherichia coli RNA Polymerase in Bacteriophage T3-Infected Cells
- 1 January 1972
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 69 (1), 162-166
- https://doi.org/10.1073/pnas.69.1.162
Abstract
A partially purified protein isolated from bacteriophage T3-infected cells of Escherichia coli B markedly inhibits the activity of E. coli RNA polymerase, slightly inhibits the activity of purified T3 polymerase, and does not inhibit the activity of either core polymerase or the ribosome-bound T3 polymerase. The properties of this protein and its mechanism of action have been studied. It appears to antagonize the action of the sigma factor component of RNA polymerase.Keywords
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