-This paper describes high-energy heavy-ion dosimetry studies with activation detectors, ionization chambers, nuclear emulsion, thermoluminescent dosimeters and X-ray film. Values of absorbed dose in tissue obtained with a nitrogen filled ionization chamber and 7LiF thermoluminescent dosimeters are compared and shown to be in agreement within 4%. As a result of this work a value for the average energy to produce an ion pair (W) in nitrogen by 250-MeV/uC6+ ions 37±1eV was determined. Values of the efficiency of 7LiF relative to 60Co gamma-rays for ions with dE/dx in the range 110–260 MeVg−1/cm2 are reported.