Some Current Concepts of Bone Physiology

Abstract

DESPITE the heightened interest and work in bone physiology during the past decade (as indicated by a sudden increase in published textbooks and symposiums)it is probably fair to state that those interested in this field are still in the stage of attempting to answer fundamental questions that have been present for a century. Although modern biophysical tools have afforded a remarkable view of the detailed structure of bone as a tissue, the mechanism of its formation, calcification and resorption is either unknown, unclear or disputed, and complete understanding is at the mercy of the most fragile hypotheses available. However, as . . .