Parental influence onX-autosome translocation-induced variegation in the mouse

Abstract

SUMMARY: Females heterozygous for theT(1; X)CtX-autosome translocation tend to have lower levels ofc-variegation when their rearrangedXis inherited from the father rather than from the mother. The difference is not due to a maternal effect. It is postulated that a paternal or parental-source effect, such as that found to modify position effect variegation inDrosophila, is operating but the possibility that a bias in the inactivation of the maternal and paternalXchromosomes is responsible cannot be ruled out.