EFFICIENT STEREOSPECIFIC SYNTHESIS OF NO-CARRIER-ADDED 2-[F-18]-FLUORO-2-DEOXY-D-GLUCOSE USING AMINOPOLYETHER SUPPORTED NUCLEOPHILIC-SUBSTITUTION
- 1 February 1986
- journal article
- research article
- Vol. 27 (2), 235-238
Abstract
An aminopolyether mediated synthesis of fluorine-18 (18F) 2-fluoro-2-deoxy-D-glucose (FDG) has been developed. The nucleophilic fluorination with accelerator-produced [18F]fluoride works at the no-carrier-added level and gives epimerically pure 2-18FDG with an uncorrected radiochemical yield of a maximum 50% in a synthesis of time of .apprx. 50 min from EOB.This publication has 11 references indexed in Scilit:
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