STUDIES ON THE EFFECT OF THYMOXYETHYLDIETHYLAMINE (929 F) AND N-DIETHYLAMINOETHYL-N-ETHYLANILINE ON GASTRIC SECRETION IN THE DOG

Abstract

A study was made of the effect of 929 F and 1571 F on the secretory response of gastric pouches in dogs. The finding of other investigators that 929 F did not inhibit the secretory response of Heidenhain pouches to histamine was confirmed. 929 F did not significantly alter the gastric secretory response of Heidenhain pouches to mecholyl chloride. 929 F inhibited the gastric secretory response of Pavlov, Heidenhain and transplanted pouches to the in-gestion of a meat meal. 1571 F inhibited the gastric secretory response of Pavlov pouches to the ingestion of a meal.