Evolutionarily Conserved and Nonconserved Cellular Localizations and Functions of Human SIRT Proteins
Top Cited Papers
- 1 October 2005
- journal article
- Published by American Society for Cell Biology (ASCB) in Molecular Biology of the Cell
- Vol. 16 (10), 4623-4635
- https://doi.org/10.1091/mbc.e05-01-0033
Abstract
Sir2 is a NAD+-dependent protein deacetylase that extends lifespan in yeast and worms. This study examines seven human proteins homologous to Sir2 (SIRT1 through SIRT7) for cellular localization, e...Keywords
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