Periventricular white matter lucencies in senile dementia of the Alzheimer type and in normal aging
- 1 August 1987
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 37 (8), 1365
- https://doi.org/10.1212/wnl.37.8.1365
Abstract
The significance of periventricular lucencies in the white matter on CT in demented patients is not understood. We studied the relationship of these changes to mental status of subjects with senile dementia of the Alzheimer type. A semiquantitative method showed more numerous and extensive lucencies in demented than in healthy elderly. Neuropathologic examination of five subjects with these changes and confirmed Alzheimer's disease revealed diffuse white matter pallor without infarction. There were no hypertensive vascular changes, although limited hyaline thickening was present.This publication has 9 references indexed in Scilit:
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