Cellular Hypoxia of Pancreatic β-Cells Due to High Levels of Oxygen Consumption for Insulin Secretion in Vitro
Open Access
- 1 April 2011
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 286 (14), 12524-12532
- https://doi.org/10.1074/jbc.m110.194738
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Hypoxia-inducible factor-1α regulates β cell function in mouse and human isletsJournal of Clinical Investigation, 2010
- PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cellsProceedings of the National Academy of Sciences, 2009
- A Role for von Hippel-Lindau Protein in Pancreatic β-Cell FunctionDiabetes, 2009
- Deletion of the von Hippel–Lindau gene in pancreatic β cells impairs glucose homeostasis in miceJournal of Clinical Investigation, 2008
- Metabolic cycling in control of glucose-stimulated insulin secretionAmerican Journal of Physiology-Endocrinology and Metabolism, 2008
- pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic β cellsGenes & Development, 2008
- Noninvasive Molecular Imaging of Hypoxia in Human Xenografts: Comparing Hypoxia-Induced Gene Expression with Endogenous and Exogenous Hypoxia MarkersCancer Research, 2008
- Islet Oxygen Consumption and Insulin Secretion Tightly Coupled to Calcium Derived from L-type Calcium Channels but Not from the Endoplasmic ReticulumPublished by Elsevier ,2008
- Novel aspects of the molecular mechanisms controlling insulin secretionThe Journal of Physiology, 2008
- Permeability of lipid membranes to dioxygenBiochemical and Biophysical Research Communications, 2004