Studies towards the total synthesis of the marine-derived immunosuppressant discodermolide; asymmetric synthesis of a C1–C8δ-lactone subunit
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 24,p. 1790-1792
- https://doi.org/10.1039/c39930001790
Abstract
The stereoselective, boron-mediated, aldol/reduction sequence, 4+5→8→9, allows an efficient asymmetric synthesis of the δ-lactone-containina. C1–C8 subunit 2 of discodermolide 1.Keywords
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