Antitumor activity of prumycin.
- 1 January 1979
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 32 (4), 347-354
- https://doi.org/10.7164/antibiotics.32.347
Abstract
The antifungal antibiotic, prumycin, was studied for antitumor activity against several tumor systems. It possesses potential antitumor activity against a well-established mouse mammary adenocarcinoma in C3H/He mice. It was also active in prolongation of the lifespan of mice bearing P-388 lymphocytic leukemia. Prumycin did not depress the white blood cell counts in the mouse peripheral blood, but severe alopecia was observed in mice treated with this agent at dosage levels near the LD50.This publication has 1 reference indexed in Scilit:
- Synthesis of 2,4-Diamino-2,4-dideoxy-l-arabinose Derivatives (Prumycin Derivatives)†Agricultural and Biological Chemistry, 1978