Screening for Acidic and Neutral Drugs by High Performance Liquid Chromatography in Post-Mortem Blood*
- 1 July 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Analytical Toxicology
- Vol. 8 (4), 173-176
- https://doi.org/10.1093/jat/8.4.173
Abstract
A procedure for screening acidic and neutral drugs in postmortem blood is presented. The procedure, which is sensitive and specific, employs high performance liquid chromatography with a reversed-phase column and an ultraviolet detector. The volume of specimen used is 1 mL. Over 40 drugs are identifiable by this technique, including analgesics, anti-inflammatory agents, barbiturates and other hypnotic-sedatives, and anti-epileptic drugs. To date, over 500 post-mortem blood specimens have been analyzed by the authors.This publication has 2 references indexed in Scilit:
- Simultaneous analysis of antiarrhythmic drugs and metabolites by high performance liquid chromatography: Interference studies and comparisons with other methodsClinical Biochemistry, 1982
- Simultaneous liquid-chromatographic determination of 12 common sedatives and hypnotics in serum.Clinical Chemistry, 1978