Somatostatin: Electron Microscope Immunohistochemical Localization in Secretory Neurons of Rat Hypothalamus
- 24 June 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 196 (4297), 1469-1470
- https://doi.org/10.1126/science.867046
Abstract
Somatostatin, the hypothalamic hormone which inhibits the secretion of growth hormone by the pituitary, has been localized in the rat hypothalamus by using electron microscope immunohistochemistry. Somatostatin occurs in secretory granules (80 to 110 nm in diameter) of a few neurons located in the hypothalamic periventricular nucleus. These observations establish the identity of neurosecretory neurons involved in the regulation of adenohypophyseal secretion.This publication has 9 references indexed in Scilit:
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