Structures of the G85R Variant of SOD1 in Familial Amyotrophic Lateral Sclerosis
Open Access
- 1 June 2008
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 283 (23), 16169-16177
- https://doi.org/10.1074/jbc.m801522200
Abstract
No abstract availableKeywords
This publication has 57 references indexed in Scilit:
- Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS modelsProceedings of the National Academy of Sciences, 2007
- Molecular dynamics using atomic-resolution structure reveal structural fluctuations that may lead to polymerization of human Cu–Zn superoxide dismutaseProceedings of the National Academy of Sciences, 2007
- Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathologyProceedings of the National Academy of Sciences, 2007
- Disease-associated Mutations at Copper Ligand Histidine Residues of Superoxide Dismutase 1 Diminish the Binding of Copper and Compromise Dimer StabilityJournal of Biological Chemistry, 2007
- Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu–Zn, Zn–Zn and As-isolated Wild-type EnzymesJournal of Molecular Biology, 2006
- Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral SclerosisJournal of Neuroscience, 2004
- An Alternative Mechanism of Bicarbonate-mediated Peroxidation by Copper-Zinc Superoxide Dismutase: RATES ENHANCED VIA PROPOSED ENZYME-ASSOCIATED PEROXYCARBONATE INTERMEDIATEPublished by Elsevier ,2003
- Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosisNature, 1993
- Determination and analysis of the 2 Å structure of copper, zinc superoxide dismutaseJournal of Molecular Biology, 1982
- An intracellular GSH-peroxidase with a lipid peroxide substrateBiochemical and Biophysical Research Communications, 1968