Introduction The surgery of duodenal ulcer has progressed from one operation to another as more and more has been learned of the pathophysiology of the disease, and as experience has been gained with various operative methods. The indications for operation have been fairly well standardized; they are hemorrhage, obstruction, perforation, and intractability. The selection of operations to be performed has been narrowed down to a comparative few. These are based on approximately the same physiologic principles, but differ in the way these principles are applied and in the operative technique of re-forming continuity of the gastrointestinal tract. We have employed 75% gastrectomy or 50% gastrectomy and section of the vagus nerves in the treatment of most of our duodenal ulcer cases in the past 10 years. In both of these operative methods gastrointestinal continuity was obtained by a gastrojejunostomy. (The anastomosis was made anterior to the colon in thin patients