Significant Variation in Serotype‐Specific Immunogenicity of the Seven‐ValentStreptococcus pneumoniaeCapsular Polysaccharide–CRM₁₉₇Conjugate Vaccine Occurs Despite Vigorous T Cell Help Induced by the Carrier Protein

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Streptococcus pneumoniae capsular polysaccharides (PnPSs) induce protective antibodies but are T cell-independent type 2 antigens and are poorly immu

Significant Variation in Serotype‐Specific Immunogenicity of the Seven‐ValentStreptococcus pneumoniaeCapsular Polysaccharide–CRM197Conjugate Vaccine Occurs Despite Vigorous T Cell Help Induced by the Carrier Protein