DIRECT CHROMOSOMAL ANALYSIS OF HUMAN-SPERMATOZOA - PRELIMINARY-RESULTS FROM 18 NORMAL MEN

  • 1 January 1982
    • journal article
    • research article
    • Vol. 34 (3), 459-468
Abstract
Chromosomal analysis of 240 spermatozoa from 18 normal men was performed using in vitro fertilization of zona-free golden hamster eggs. The frequency of chromosome abnormalities in this population was 9.2% (22/240). Of the abnormal complements, 18 were aneuploid (13 hyperploid and 5 hypoploid) and 4 had a chromosome break. The sex ratio of Y-bearing to X-bearing sperm was 0.68. The frequency and type of sperm chromosome abnormalities is compared with those seen in spontaneous abortions.