Molecular hybridization to meiotic chromosomes in man reveals sequence arrangement on the No. 9 chromosome and provides clues to the nature of “parameres”
- 1 January 1986
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 41 (2), 89-95
- https://doi.org/10.1159/000132209
Abstract
In situ hybridization of male human meiotic material has been used to elucidate the molecular organization of the centromeric region of human chromosome 9. The use of two cloned DN A sequences has shown that the centromere and the secondary constriction of this chromosome contain two separate repeated DNA families. The secondary constriction organizes into “paramere” bodies during pachytene. The individual parameres are comprised of one family of repeated DNA sequences.Keywords
This publication has 18 references indexed in Scilit:
- Construction and characterization of the hybrid bacteriophage lambda Charon vectors for DNA cloningJournal of Virology, 1979
- Specific arrangements of human satellite III DNA sequences in human chromosomesChromosoma, 1979
- Localisation of a male-specific DNA fragment to a sub-region of the human Y chromosomeNature, 1978
- Modification of DAPI banding on human chromosomes by prestaining with a DNA-binding oligopeptide antibiotic, distamycin AExperimental Cell Research, 1978
- Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase IJournal of Molecular Biology, 1977
- Screening λgt Recombinant Clones by Hybridization to Single Plaques in SituScience, 1977
- Repeated sequence specific to human malesNature, 1976
- Kinetics of renaturation of DNAJournal of Molecular Biology, 1968
- An Air-Drying Method for Meiotic Preparations from Mammalian TestesCytogenetic and Genome Research, 1964
- Carbol Fuchsin as A Stain for Human ChromosomesStain Technology, 1961