Infantile Cortical Hyperostosis

Abstract

THE syndrome that has become known as infantile cortical hyperostosis, after the suggestion of Caffey and Silverman,¹ is characterized by the usually sudden onset of swelling of the face, thorax or extremities, hyperirritability, fever, fluctuating course and roentgenographic evidence of periosteal new-bone formation. Probably the first case was described by Roske,² but the syndrome was not appreciated until the publication of the descriptions of the clinical and roentgenologic picture.^{1 , 3 , 4} There are now over 60 cases in the literature. Sherman and Hellyer⁵ reviewed their x-ray films taken of infants during the preceding twenty years and found no case of infantile cortical . . .