Increased Physical Stability and Improved Dissolution Properties of Itraconazole, a Class II Drug, by Solid Dispersions that Combine Fast‐ and Slow‐Dissolving Polymers
- 1 January 2004
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical Sciences
- Vol. 93 (1), 124-131
- https://doi.org/10.1002/jps.10522
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- Thermal Properties of Hot-Stage Extrudates of Itraconazole and Eudragit E100. Phase separation and polymorphismJournal of Thermal Analysis and Calorimetry, 2002
- The mechanisms of drug release from solid dispersions in water-soluble polymersInternational Journal of Pharmaceutics, 2001
- Investigation of thermal properties of glassy itraconazole: identification of a monotropic mesophaseThermochimica Acta, 2001
- Characterization of glassy itraconazole: a comparative study of its molecular mobility below Tg with that of structural analogues using MTDSCInternational Journal of Pharmaceutics, 2001
- Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25European Journal of Pharmaceutical Sciences, 2000
- Improving drug solubility for oral delivery using solid dispersionsEuropean Journal of Pharmaceutics and Biopharmaceutics, 2000
- Physical Properties of Solid Molecular Dispersions of Indomethacin with Poly(vinylpyrrolidone) and Poly(vinylpyrrolidone-co-vinyl-acetate) in Relation to Indomethacin CrystallizationPharmaceutical Research, 1999
- A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo BioavailabilityPharmaceutical Research, 1995
- Viscosity and glass temperature relations for polymer‐diluent systemsJournal of Polymer Science, 1961
- Ideal copolymers and the second‐order transitions of synthetic rubbers. i. non‐crystalline copolymersJournal of Chemical Technology & Biotechnology, 1952