This is a report on 77 patients with pemphigus treated in the dermatologic service1of the New York City Hospital during the past twenty years. The cause of pemphigus is still unproved, and practically all therapeutic measures have thus far been empiric. Opinions vary concerning the prognosis of this disease. There are many dermatologists who believe that all patients with true pemphigus die within a short period after onset of the disease (the time varying from a few months to some years), although they admit that remissions may occur during this period. They believe that so-called cured conditions or conditions of longer duration are not pemphigus but are bullous eruptions of dermatitis herpetiformis, erythema multiforme, lupus erythematosus disseminatus or drug eruptions. We therefore felt that this presentation containing data obtained from cases of pemphigus, such as race, previous history, symptoms and signs, laboratory findings, results of biopsies, duration and