Asymmetric reduction of aromatic ketones by sodium borohydride in the presence of bovine serum albumin

1 January 1978

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 21,p. 926-927
https://doi.org/10.1039/c39780000926

Abstract

Bovine serum albumin was used to provide a chiral template for asymmetric reduction of aromatic ketones by the achiral NaBH₄, and substantial (20–80%) enantiomeric excesses were obtained in the product alcohols.

Keywords

SODIUM
AROMATIC KETONES
SERUM ALBUMIN
BOVINE SERUM
SUBSTANTIAL
ENANTIOMERIC
NABH4

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