Hepatitis B virus DNA Sequences in Lymphoid Cells from Patients with AIDS and AIDS-Related Complex
- 9 August 1985
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 229 (4713), 561-563
- https://doi.org/10.1126/science.2410981
Abstract
A lymphotropic virus HTLV-III/LAV was recently identified as the etiologic agent of the acquired immune deficiency syndrome (AIDS). In a study of concomitant hepatitis B infections in patients with AIDS or the AIDS-related complex, DNA sequences of hepatitis B virus (HBV) were found in fresh and cultured lymphocytes from patients with AIDS even in the absence of conventional HBV serological markers. Furthermore, the restriction DNA pattern was consistent with the integration of the viral DNA. These results should prompt additional studies to reevaluate a possible role of HBV as a cofactor in AIDS in addition to the HTLV-III/LAV causal agent.This publication has 25 references indexed in Scilit:
- Molecular cloning of AIDS-associated retrovirusNature, 1984
- A Pathogenic Retrovirus (HTLV-III) Linked to AIDSNew England Journal of Medicine, 1984
- Molecular cloning and characterization of the HTLV-III virus associated with AIDSNature, 1984
- A New Basis for Recognizing the Paleocene/Eocene Boundary in Western Interior North AmericaScience, 1984
- Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDSScience, 1984
- Acquired Immunodeficiency Syndrome in InfantsNew England Journal of Medicine, 1984
- Acquired Immunodeficiency Syndrome (AIDS) Associated with TransfusionsNew England Journal of Medicine, 1984
- Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)Science, 1983
- Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigenNature, 1979
- Detection of specific sequences among DNA fragments separated by gel electrophoresisJournal of Molecular Biology, 1975