Preparation of Nα-(t-Butoxycarbonyl)-O-(dibenzylphosphono)-L-serine

Abstract

The protected phosphoserine synthon Nα-(t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine was prepared in three steps. Stability studies on the phosphorylating agent dibenzyl phosphorochloridate were performed by 31P n.m.r. spectroscopy.