Effect of Oral Milrinone on Mortality in Severe Chronic Heart Failure
Open Access
- 21 November 1991
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 325 (21), 1468-1475
- https://doi.org/10.1056/nejm199111213252103
Abstract
Milrinone, a phosphodiesterase inhibitor, enhances cardiac contractility by increasing intracellular levels of cyclic AMP, but the long-term effect of this type of positive inotropic agent on the survival of patients with chronic heart failure has not been determined.Keywords
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