A human lymphoid- specific transcription factor that activates immunoglobulin genes is a homoeobox protein
- 1 December 1988
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 336 (6199), 551-557
- https://doi.org/10.1038/336551a0
Abstract
The human lymphoid-specific transcription factor OTF-2 contains a homoeodomain that is required for DNA binding and binds specifically to DNA elements that are recognized by Drosophila homoeodomain proteins, suggesting coevolutionary relationships between mammalian and invertebrate homoeodomain proteins and their DNA recognition elements.Keywords
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